Manchester United makes Amad Diallo his first Premier League start of the year.
Sofyan Amrabat and Scott McTominay, who is back from injury, join the forward.
Bruno Fernandes, who resumed training this week after missing Crystal Palace’s 4-0 loss, is not included in the starting lineup. Mason Mount’s injury prevents him from playing.
Manchester United starting eleven: Onana, Dalot, Evans, Wan-Bissaka, Amrabat, Diallo, McTominay, Garnacho, Hojlund.
Subs: Wheatley, Amass, Ogunneye, Forson, Collyer, Antony, Eriksen, and Kambwala.
Arsenal, on the other hand, starts with the same lineup as their most recent 3-0 victory over Bournemouth.
Midweek, Takehiro Tomiyasu and Bukayo Saka were questioned about their fitness, but they have since recovered to start for the team.
Arsenal starting lineup: Raya, White, Saliba, Gabriel, Odegaard, Partey, Rice, Saka, Havertz, Trossard, Tomiyasu.
Subs: Jorginho, Vieira, Zinchenko, Nketiah, Kiwior, Ramsdale, Gabriel Jesus, Smith Rowe, Martinelli, and Nketiah.
